Lou and Bobo used to be best friends, until Lou took something that wasn't his, and incurred Bobo's everlasting hatred. Lou wanted to take over the town Purgatory and have the human inhabitants as slaves, Bobo opposed this and the close friendship was over, but before Lou left Puragatory he took a weapon from Bobo. Earp heirs have came before but Lou never revealed himself to them.
Lou is associated to the wolf and was located at the Pine Barrens. It was revealed that the weapon Lou took was Willa Earp.
Lou was killed by Peacemaker wielded by Willa Earp.
- His first wife, Tadewi was a horse-whisperer of sorts according to Dolls, an actual Skin-walker, who took the shape of a wolf. He had been using her as a weapon for over 100 years.